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Select item 111253591.

Exploring the Potential Biological Activities of Pyrazole-Based Schiff Bases as Anti-Diabetic, Anti-Alzheimer’s, Anti-Inflammatory, and Cytotoxic Agents: In Vitro Studies with Computational Predictions

Ahmed M. Naglah, Abdulrahman A. Almehizia, Asma S. Al-Wasidi, Amirah Senaitan Alharbi, Mohammed H. Alqarni, Ashraf S. Hassan, Wael M. Aboulthana

Pharmaceuticals (Basel) 2024 May; 17(5): 655. Published online 2024 May 17. doi: 10.3390/ph17050655

PMCID:: PMC11125359

Abstract Article PDF–4.2M

Select item 111253402.

A Carbon 21 Steroidal Glycoside with Pregnane Skeleton from Cynanchum atratum Bunge Promotes Megakaryocytic and Erythroid Differentiation in Erythroleukemia HEL Cells through Regulating Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway

Jue Yang, Chaolan Pan, Yang Pan, Anlin Hu, Peng Zhao, Meijun Chen, Hui Song, Yanmei Li, Xiaojiang Hao

Pharmaceuticals (Basel) 2024 May; 17(5): 628. Published online 2024 May 14. doi: 10.3390/ph17050628

PMCID:: PMC11125340

Abstract Article PDF–22M

Select item 111252403.

Impact of Cuminaldehyde and Indomethacin Co-Administration on Inflammatory Responses in MIA-Induced Osteoarthritis in Rats

Sebastião Vieira de Morais, Gustavo Pereira Calado, Rafael Cardoso Carvalho, João Batista Santos Garcia, Thyago Moreira de Queiroz, Antonio José Cantanhede Filho, Alberto Jorge Oliveira Lopes, Maria do Socorro de Sousa Cartágenes, Gerson Ricardo de Souza Domingues

Pharmaceuticals (Basel) 2024 May; 17(5): 630. Published online 2024 May 14. doi: 10.3390/ph17050630

PMCID:: PMC11125240

Abstract Article PDF–2.4M

Select item 111250184.

Using In Silico Molecular Docking to Explain Differences in Receptor Binding Behavior of HHC and THCV Isomers: Revealing New Binding Modes

Mehdi Haghdoost, Yossef López de los Santos, Megan Brunstetter, Morgan L. Ferretti, Matthew Roberts, Marcel O. Bonn-Miller

Pharmaceuticals (Basel) 2024 May; 17(5): 637. Published online 2024 May 15. doi: 10.3390/ph17050637

PMCID:: PMC11125018

Abstract Article PDF–4.1M

Select item 111250125.

Evaluating the Role of Neddylation Modifications in Kidney Renal Clear Cell Carcinoma: An Integrated Approach Using Bioinformatics, MLN4924 Dosing Experiments, and RNA Sequencing

Dequan Liu, Guangzhen Wu, Shijin Wang, Xu Zheng, Xiangyu Che

Pharmaceuticals (Basel) 2024 May; 17(5): 635. Published online 2024 May 15. doi: 10.3390/ph17050635

PMCID:: PMC11125012

Abstract Article PDF–8.3M

Select item 111248226.

Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor

Aya Soudi, Onur Bender, Ismail Celik, Amer Ali Abd El-Hafeez, Rumeysa Dogan, Arzu Atalay, Eslam B. Elkaeed, Aisha A. Alsfouk, Elshimaa M. N. Abdelhafez, Omar M. Aly, Wolfgang Sippl, Taha F. S. Ali

Pharmaceuticals (Basel) 2024 May; 17(5): 659. Published online 2024 May 20. doi: 10.3390/ph17050659

PMCID:: PMC11124822

Abstract Article PDF–3.7M

Select item 111245307.

Therapeutic Drug Monitoring in Psychiatry: Enhancing Treatment Precision and Patient Outcomes

Letizia Biso, Stefano Aringhieri, Marco Carli, Marco Scarselli, Biancamaria Longoni

Pharmaceuticals (Basel) 2024 May; 17(5): 642. Published online 2024 May 16. doi: 10.3390/ph17050642

PMCID:: PMC11124530

Abstract Article PDF–940K

Select item 111245298.

Unveiling the Role of Tryptophan 2,3-Dioxygenase in the Angiogenic Process

Marta Cecchi, Cecilia Anceschi, Angela Silvano, Maria Luisa Coniglio, Aurora Chinnici, Lucia Magnelli, Andrea Lapucci, Anna Laurenzana, Astrid Parenti

Pharmaceuticals (Basel) 2024 May; 17(5): 558. Published online 2024 Apr 27. doi: 10.3390/ph17050558

PMCID:: PMC11124529

Abstract Article PDF–5.6M

Select item 111245259.

Pharmacokinetic–Pharmacodynamic Correlation Analysis of Rhodiola crenulata in Rats with Myocardial Ischemia

Zhixin Jia, Guoming Zou, Yongyan Xie, Enning Zhang, Mureziya Yimingjiang, Xianlong Cheng, Cong Fang, Feng Wei

Pharmaceuticals (Basel) 2024 May; 17(5): 595. Published online 2024 May 7. doi: 10.3390/ph17050595

PMCID:: PMC11124525

Abstract Article PDF–2.1M

Select item 1112452410.

Patchouli Alcohol Protects the Heart against Diabetes-Related Cardiomyopathy through the JAK2/STAT3 Signaling Pathway

Lijun Ji, Shuaijie Lou, Yi Fang, Xu Wang, Weiwei Zhu, Guang Liang, Kwangyoul Lee, Wu Luo, Zaishou Zhuang

Pharmaceuticals (Basel) 2024 May; 17(5): 631. Published online 2024 May 14. doi: 10.3390/ph17050631

PMCID:: PMC11124524

Abstract Article PDF–3.2M

Select item 1112450711.

Synthesis and Evaluation of Novel ⁶⁸Ga-Labeled [D-Phe⁶,Leu¹³ψThz¹⁴]bombesin(6-14) Analogs for Cancer Imaging with Positron Emission Tomography

Lei Wang, Chao-Cheng Chen, Zhengxing Zhang, Hsiou-Ting Kuo, Chengcheng Zhang, Nadine Colpo, Helen Merkens, François Bénard, Kuo-Shyan Lin

Pharmaceuticals (Basel) 2024 May; 17(5): 621. Published online 2024 May 11. doi: 10.3390/ph17050621

PMCID:: PMC11124507

Abstract Article PDF–3.3M

Select item 1112449212.

Classical and Novel Lipid-Lowering Therapies for Diabetic Patients with Established Coronary Artery Disease or High Risk of Coronary Artery Disease—A Narrative Clinical Review

Nikolaos Velidakis, Panagiotis Stachteas, Evangelia Gkougkoudi, Christodoulos Papadopoulos, Nikolaos P. E. Kadoglou

Pharmaceuticals (Basel) 2024 May; 17(5): 568. Published online 2024 Apr 29. doi: 10.3390/ph17050568

PMCID:: PMC11124492

Abstract Article PDF–1.2M

Select item 1112449013.

Structure–Activity Relationship of Synthetic Linear KTS-Peptides Containing Meta-Aminobenzoic Acid as Antagonists of α1β1 Integrin with Anti-Angiogenic and Melanoma Anti-Tumor Activities

Majdi Saleem Naamneh, Tatjana Momic, Michal Klazas, Julius Grosche, Johannes A. Eble, Cezary Marcinkiewicz, Netaly Khazanov, Hanoch Senderowitz, Amnon Hoffman, Chaim Gilon, Jehoshua Katzhendler, Philip Lazarovici

Pharmaceuticals (Basel) 2024 May; 17(5): 549. Published online 2024 Apr 24. doi: 10.3390/ph17050549

PMCID:: PMC11124490

Abstract Article PDF–3.5M

Select item 1112448014.

Testing of Anti-EMT, Anti-Inflammatory and Antibacterial Activities of 2′,4′-Dimethoxychalcone

Peiling Zhao, Mengzhen Xu, Kai Gong, Kaihui Lu, Chen Ruan, Xin Yu, Jiang Zhu, Haixing Guan, Qingjun Zhu

Pharmaceuticals (Basel) 2024 May; 17(5): 653. Published online 2024 May 17. doi: 10.3390/ph17050653

PMCID:: PMC11124480

Abstract Article PDF–13M

Select item 1112442715.

Methyl-Containing Pharmaceuticals

Davide Illuminati, Anna Fantinati

Pharmaceuticals (Basel) 2024 May; 17(5): 563. Published online 2024 Apr 28. doi: 10.3390/ph17050563

PMCID:: PMC11124427

Article PDF–180K

Select item 1112442116.

Structural Modification and Optimisation of Hyperoside Oriented to Inhibit TGF-β-Induced EMT Activity in Alveolar Epithelial Cells

Ziye Gao, Mengzhen Xu, Chuanguo Liu, Kai Gong, Xin Yu, Kaihui Lu, Jiang Zhu, Haixing Guan, Qingjun Zhu

Pharmaceuticals (Basel) 2024 May; 17(5): 584. Published online 2024 May 2. doi: 10.3390/ph17050584

PMCID:: PMC11124421

Abstract Article PDF–5.2M

Select item 1112441317.

Synthesis, Antibacterial Effects, and Toxicity of Licochalcone C

Patrick Rômbola Ozanique, Alvaro Luiz Helena, Ralciane de Paula Menezes, Daniela Silva Gonçalves, Mariana Brentini Santiago, Guilherme Dilarri, Janaína de Cássia Orlandi Sardi, Henrique Ferreira, Carlos Henrique Gomes Martins, Luis Octávio Regasini

Pharmaceuticals (Basel) 2024 May; 17(5): 634. Published online 2024 May 14. doi: 10.3390/ph17050634